Mitchell K Higashi, PhD
Adjunct Full Instructional Professor
Department:
Pharmaceutical Outcomes & Policy
Business Phone:
(609) 558-7699
Business Email:
mhigashi@ufl.edu
About Mitchell K Higashi
Mitch Higashi, PhD, is the Associate Chief Science Officer for ISPOR—The Professional Society for Health Economics and Outcomes Research, where he oversees science and content strategies, collaborates with special interest groups and health policy working groups, and advances initiatives to increase awareness and application of health economics and outcomes research (HEOR) globally.
With a robust background in HEOR, Dr. Higashi previously served as Senior Vice President at GeneDx, implementing market access and real-world evidence programs for genomic solutions, algorithms, and pharma partners. At Bristol Myers Squibb, he led a cross-portfolio team, contributing to significant FDA filings and global health technology assessments. His earlier roles include Chief Economist at GE Healthcare and US Head of HEOR at GlaxoSmithKline.
Dr. Higashi earned his PhD from the University of Washington and completed the Advanced Management Program at The Wharton School.
Teaching Profile
Courses Taught
2024
PHA6286 Pharmaceutical Microeconomics
Publications
2023
Analysis of real-world data to investigate evolving treatment sequencing patterns in advanced non-small cell lung cancers and their impact on survival.
Journal of thoracic disease.
15(5):2438-2449
[DOI] 10.21037/jtd-22-1481.
[PMID] 37324065.
2023
Detecting Ground Glass Opacity Features in Patients With Lung Cancer: Automated Extraction and Longitudinal Analysis via Deep Learning-Based Natural Language Processing.
JMIR AI.
2
[DOI] 10.2196/44537.
[PMID] 38875565.
2021
Evolving use of real-world evidence in the regulatory process: a focus on immuno-oncology treatment and outcomes.
Future oncology (London, England).
17(3):333-347
[DOI] 10.2217/fon-2020-0591.
[PMID] 33074018.
2017
A proposed approach for quantitative benefit-risk assessment in diagnostic radiology guideline development: the American College of Radiology Appropriateness Criteria Example.
Journal of evaluation in clinical practice.
23(1):128-138
[DOI] 10.1111/jep.12635.
[PMID] 27762080.
2017
Toward a Framework for Benefit-Risk Assessment in Diagnostic Imaging: Identifying Scenario-specific Criteria.
Academic radiology.
24(5):538-549
[DOI] 10.1016/j.acra.2017.02.002.
[PMID] 28372958.
2017
Using the Analytic Hierarchy Process for Prioritizing Imaging Tests in Diagnosis of Suspected Appendicitis.
Academic radiology.
24(5):530-537
[DOI] 10.1016/j.acra.2017.01.001.
[PMID] 28363670.
2016
Transforming Healthcare Delivery: Integrating Dynamic Simulation Modelling and Big Data in Health Economics and Outcomes Research.
PharmacoEconomics.
34(2):115-26
[DOI] 10.1007/s40273-015-0330-7.
[PMID] 26497003.
2015
Applying dynamic simulation modeling methods in health care delivery research-the SIMULATE checklist: report of the ISPOR simulation modeling emerging good practices task force.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.
18(1):5-16
[DOI] 10.1016/j.jval.2014.12.001.
[PMID] 25595229.
2015
Selecting a dynamic simulation modeling method for health care delivery research-part 2: report of the ISPOR Dynamic Simulation Modeling Emerging Good Practices Task Force.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.
18(2):147-60
[DOI] 10.1016/j.jval.2015.01.006.
[PMID] 25773550.
2014
Applying quantitative benefit-risk analysis to aid regulatory decision making in diagnostic imaging: methods, challenges, and opportunities.
Academic radiology.
21(9):1138-43
[DOI] 10.1016/j.acra.2014.05.006.
[PMID] 25107866.
2013
Feasibility of an online mindfulness program for stress management–a randomized, controlled trial.
Annals of behavioral medicine : a publication of the Society of Behavioral Medicine.
46(2):137-48
[DOI] 10.1007/s12160-013-9490-x.
[PMID] 23632913.
2011
Innovation in diagnostic imaging services: assessing the potential for value-based reimbursement.
Academic radiology.
18(9):1109-14
[DOI] 10.1016/j.acra.2011.04.007.
[PMID] 21703880.
2009
Optimizing CAD diagnosis in China with CT angiography.
Journal of cardiovascular computed tomography.
3(3):153-8
[DOI] 10.1016/j.jcct.2009.03.005.
[PMID] 19394919.
2005
A cost-effectiveness analysis of antibiotic therapy in macrolide-resistant community-acquired pneumonia.
Managed care interface.
18(10):36-44
[PMID] 16265933.
2005
CYP2C9 haplotype structure in European American warfarin patients and association with clinical outcomes.
Clinical pharmacology and therapeutics.
77(5):353-64
[PMID] 15900281.
2005
The quality of life impact of acute exacerbations of chronic bronchitis (AECB): a literature review.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation.
14(2):329-47
[PMID] 15892423.
2004
Health economic evaluation of non-melanoma skin cancer and actinic keratosis.
PharmacoEconomics.
22(2):83-94
[PMID] 14731050.
2004
The workplace impact of acute exacerbations of chronic bronchitis (AECB); A literature review.
COPD.
1(2):249-54
[PMID] 17136991.
2003
Managed care in the genomics era: assessing the cost effectiveness of genetic tests.
The American journal of managed care.
9(7):493-500
[PMID] 12866628.
2003
The economic impact of acute exacerbations of chronic bronchitis in the United States and Canada: a literature review.
Journal of managed care pharmacy : JMCP.
9(4):353-9
[DOI] 10.18553/jmcp.2003.9.4.353.
[PMID] 14613454.
2002
Association between CYP2C9 genetic variants and anticoagulation-related outcomes during warfarin therapy.
JAMA.
287(13):1690-8
[PMID] 11926893.
2002
The cost-effectiveness of interleukin-1 genetic testing for periodontal disease.
Journal of periodontology.
73(12):1474-84
[PMID] 12546098.
Education
Advanced Management Program
2005
·
The Wharton School
PhD, Health Economics and Outcomes Research
2001
·
University of Washington
Contact Details
Phones:
- Business:
- (609) 558-7699
Emails:
- Business:
- mhigashi@ufl.edu
Addresses:
- Business Street:
-
682 CONESTOGA RD
VILLANOVA PA 19085