This course covers the essential concepts related to research design and methodology utilized in clinical research. Students need to become critical evaluators of research and prepare for conducting research that follows appropriate standards from the initial concept of an investigator to the publication and defense of research results. Focus is on understanding each component of the research process, including how to formulate a research question, develop and formalize hypotheses, analyze measurement instruments, protocol development, protocol management, collect relevant data, data analysis, and project management. The key focus is to understand these components while preserving the ethical guidelines of human subject research. The primary goal of this course is for students to gain a more complete understanding of the research process and steps in clinical research protocols to allow them to critically analyze published research and/or be able to conduct independent research. This course will not focus on the statistical analysis or the actual use of statistical tests, which are covered in the statistics course for this program.